Using a special probiotic to prevent Salmonella infections in poultry
Official title: Influence of an E. coli hyperadherent probiotic on Salmonella intestinal colonization
Funded at University of Iowa · NIH-11134572 · Data updated 2026-11-12
This study is looking at how a special probiotic strain of E. coli can help keep harmful Salmonella bacteria from taking over in chickens, which could make poultry products safer for you to eat.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | July 8, 2024 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $77,750 |
| NIH project number | 5R03AI180684-02 |
| Project ID | NIH-11134572 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include consumers of poultry products and individuals at risk of Salmonella infections.
✕Less likely to help
Patients who do not consume poultry or are not at risk for Salmonella infections may not benefit from this research.
What this research studies
This research investigates how a specially engineered probiotic strain of E. coli can help reduce Salmonella colonization in poultry. By enhancing the binding ability of this probiotic, the goal is to outcompete harmful Salmonella bacteria in the intestines of birds. This approach aims to improve food safety by decreasing the presence of Salmonella in poultry products, which are major sources of food-borne illness. The study will involve optimizing the probiotic's effectiveness and testing its ability to prevent Salmonella colonization.
Why it matters
Potential benefit: If successful, this research could lead to safer poultry products and a reduction in food-borne illnesses caused by Salmonella.
How similar studies have gone: Previous research has shown promise in using probiotics to combat bacterial infections, suggesting potential success for this novel approach.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Jones, Bradley D — University of Iowa
- Study coordinator: Jones, Bradley D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.