Using a special heart pump to help children with severe heart failure
Official title: 1/2 Circulatory Support in Pediatric Heart Failure Patients Using the Jarvik 2015 LVAD: A Pivotal Trial
Funded at Stanford University · NIH-10591344 · Data updated 2026-11-12
This study is looking at how well the Jarvik 2015 heart pump can help kids with severe heart failure who haven't found relief from other treatments, with the hope that it can improve their lives while they wait for a heart transplant.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,073,956 |
| NIH project number | 1UG3HL163311-01A1 |
| Project ID | NIH-10591344 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are hospitalized children under 21 years old who are experiencing severe heart failure and have not responded to medical therapy.
✕Less likely to help
Patients with heart failure who are not hospitalized or those who are not candidates for heart transplantation may not benefit from this research.
What this research studies
This research investigates the use of the Jarvik 2015 left ventricular assist device (LVAD) as a temporary solution for children suffering from severe heart failure who have not responded to other treatments. The trial will involve 22 hospitalized children and aims to gather important safety and effectiveness data to support FDA approval of this device. By providing a bridge to heart transplantation, this device could improve the quality of life for these young patients. The study will be conducted across multiple centers to ensure a diverse patient population.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for children with severe heart failure, potentially improving their chances of recovery and quality of life.
How similar studies have gone: Previous research has shown success with similar heart pump devices in adult populations, but this specific application in pediatric patients is novel.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Almond, Christopher — Stanford University
- Study coordinator: Almond, Christopher
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.