Using a special heart pump to help children with severe heart failure

1/2 Circulatory Support in Pediatric Heart Failure Patients Using the Jarvik 2015 LVAD: A Pivotal Trial

NIH-funded research Stanford University · NIH-10591344

This study is looking at how well the Jarvik 2015 heart pump can help kids with severe heart failure who haven't found relief from other treatments, with the hope that it can improve their lives while they wait for a heart transplant.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10591344 on NIH RePORTER

What this research studies

This research investigates the use of the Jarvik 2015 left ventricular assist device (LVAD) as a temporary solution for children suffering from severe heart failure who have not responded to other treatments. The trial will involve 22 hospitalized children and aims to gather important safety and effectiveness data to support FDA approval of this device. By providing a bridge to heart transplantation, this device could improve the quality of life for these young patients. The study will be conducted across multiple centers to ensure a diverse patient population.

Who could benefit from this research

Good fit: Ideal candidates for this research are hospitalized children under 21 years old who are experiencing severe heart failure and have not responded to medical therapy.

Not a fit: Patients with heart failure who are not hospitalized or those who are not candidates for heart transplantation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for children with severe heart failure, potentially improving their chances of recovery and quality of life.

How similar studies have performed: Previous research has shown success with similar heart pump devices in adult populations, but this specific application in pediatric patients is novel.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.