Using a single pill to improve heart failure treatment in underserved populations
Polypill strategy for the evidence-based management of heart failure with reduced ejection fraction in an underserved patient population
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11015042
This study is testing a new all-in-one pill to help make heart failure treatment easier for patients, especially those from low-income and diverse backgrounds, so they can take their medicine more regularly and feel better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11015042 on ClinicalTrials.gov |
What this research studies
This research investigates a new approach to treating heart failure with reduced ejection fraction (HFrEF) by using a polypill that combines multiple medications into one. The goal is to simplify treatment for patients, particularly those from low-income and racially diverse backgrounds, who often face barriers to accessing multiple medications. By reducing the number of pills patients need to take, the study aims to improve adherence to treatment and ultimately enhance health outcomes. The research will be conducted at a single center in Dallas, focusing on patients who are typically under-treated due to socioeconomic challenges.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with heart failure and reduced ejection fraction, particularly those from low-income and racially diverse backgrounds.
Not a fit: Patients who do not have heart failure or those who are not part of the targeted underserved populations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the management of heart failure in underserved populations, leading to better health outcomes and reduced mortality rates.
How similar studies have performed: Previous research has shown that polypill strategies can improve medication adherence and health outcomes, suggesting potential success for this approach in heart failure management.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PANDEY, AMBARISH — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: PANDEY, AMBARISH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.