Using a polymer-based system to enhance spinal cord repair
Official title: Promoting spinal cord repair using a polymer-based drug delivery system
Funded at Ohio State University · NIH-11139661 · Data updated 2026-11-12
This study is exploring a new way to help heal spinal cord injuries by using a special delivery system to target important pathways in the nervous system, which could help improve recovery and restore movement for people affected by these injuries.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | April 25, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $184,837 |
| NIH project number | 1R21NS139109-01A1 |
| Project ID | NIH-11139661 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced traumatic spinal cord injuries.
✕Less likely to help
Patients with non-traumatic spinal cord conditions or those who are not within the specified age range may not benefit from this research.
What this research studies
This research investigates a novel approach to promote spinal cord repair following traumatic injuries. It focuses on using a polymer-based drug delivery system to target specific neuronal pathways that are crucial for recovery. By blocking certain proteins that hinder axon regeneration, the study aims to improve the healing process and restore function in affected areas. Patients may benefit from this innovative treatment strategy if it proves effective in clinical applications.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery outcomes for individuals with spinal cord injuries.
How similar studies have gone: Previous studies have shown promising results with similar pharmacological approaches in animal models, suggesting potential for success in human applications.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Tedeschi, Andrea — Ohio State University
- Study coordinator: Tedeschi, Andrea
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.