Using a plant-based treatment for endometriosis

Phytotherapy for Endometriosis

NIH-funded research Texas A&m University · NIH-11094125

This study is looking at how a natural plant called Withania somnifera might help women with endometriosis by reducing pain and stopping the growth of endometriosis-related tissue, offering a new treatment option that doesn't involve steroids.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTexas A&m University NIH-funded
Lab location1 site (College Station, United States)
Project IDNIH-11094125 on NIH RePORTER

What this research studies

This research investigates the potential of Withania somnifera, a medicinal plant, to treat endometriosis, a condition that causes chronic pelvic pain and infertility in women. The study aims to understand how Withaferin-A, an active compound in the plant, can suppress the growth of endometriotic lesions and alleviate pain. By exploring the molecular and cellular mechanisms involved, the research seeks to provide a non-steroidal therapy option for women suffering from this debilitating condition. Patients may be involved in preclinical trials to assess the effectiveness of this treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of reproductive age who are diagnosed with endometriosis and experience chronic pelvic pain or infertility.

Not a fit: Patients who do not have endometriosis or those who are not experiencing symptoms related to the condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a new, effective treatment option for women suffering from endometriosis-related pain and infertility.

How similar studies have performed: While the use of Withania somnifera has shown promise in treating various inflammatory conditions, this specific application for endometriosis is novel and has not been extensively tested.

Where this research is happening

College Station, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.