Using a new type of plasma to prevent dental cavities

Feasibility of novel Fluorine Non-thermal plasma for dental caries control

NIH-funded research University of Tennessee Health Sci Ctr · NIH-10892292

This study is exploring a new way to help prevent cavities by using a special technique that delivers fluoride more effectively to strengthen your teeth, so you can enjoy better dental health and fewer cavities.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-10892292 on NIH RePORTER

What this research studies

This research investigates the use of fluorine non-thermal plasma (FNTP) as a novel method for controlling dental caries. The approach focuses on delivering fluoride more effectively into tooth enamel, enhancing its ability to remineralize and resist decay. By utilizing FNTPs, the study aims to overcome the limitations of traditional fluoride delivery methods, which often fail to penetrate deeper layers of enamel. Patients may benefit from improved dental health and reduced incidence of cavities through this innovative technology.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 21 and older who are at risk for dental caries.

Not a fit: Patients with existing severe dental issues or those who do not have access to dental care may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention of dental cavities, improving oral health for patients.

How similar studies have performed: While the use of FNTPs is a novel approach, previous studies have shown promise in using plasma technologies for dental applications.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.