Using a new MRI method to improve liver cancer screening in patients with cirrhosis
Abbreviated MRI for HCC screening in cirrhotic patients
This study is testing a new type of MRI that could help find liver cancer earlier in people with cirrhosis, and it's looking for 820 participants to see if this method works better than the usual ultrasound screenings.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10874731 on NIH RePORTER |
What this research studies
This research investigates a novel abbreviated magnetic resonance imaging (AMRI) technique designed to enhance the detection of hepatocellular carcinoma (HCC) in patients with cirrhosis. The study aims to compare the effectiveness of this new MRI method against traditional ultrasound screenings, which have shown limited accuracy in this patient population. By utilizing a specific imaging sequence after administering a contrast agent, the researchers hope to achieve higher sensitivity for early-stage HCC detection. The study will involve multiple centers and aims to enroll 820 participants to validate the performance of this new screening approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with cirrhosis.
Not a fit: Patients without cirrhosis or those with other types of liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of liver cancer in cirrhotic patients, potentially improving treatment outcomes and survival rates.
How similar studies have performed: Previous studies have shown promising results with similar MRI techniques, indicating potential for improved cancer detection in high-risk populations.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Taouli, Bachir — Icahn School of Medicine at Mount Sinai
- Study coordinator: Taouli, Bachir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.