Using a new heart pump to help children with severe heart failure

2/2 Circulatory Support in Pediatric Heart Failure Patients Using the Jarvik 2015 LVAD: A Pivotal Trial

NIH-funded research New England Research Institutes, INC. · NIH-10591083

This study is looking at how well the Jarvik 2015 heart pump can help kids with severe heart failure who haven't improved with regular treatments, giving them a better chance while they wait for a heart transplant.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew England Research Institutes, INC. NIH-funded
Lab location1 site (Wilmington, UNITED STATES)
Project IDNIH-10591083 on NIH RePORTER

What this research studies

This research investigates the use of the Jarvik 2015 left ventricular assist device (LVAD) as a temporary solution for children suffering from severe heart failure who do not respond to standard treatments. The study will involve multiple centers and aims to gather important safety and effectiveness data to support the device's approval for use in pediatric patients. By providing a bridge to heart transplantation, this device could potentially improve the quality of life for these young patients while they await a suitable donor heart.

Who could benefit from this research

Good fit: Ideal candidates for this research are hospitalized children with severe heart failure who have not responded to medical therapy and are awaiting heart transplantation.

Not a fit: Patients with heart failure who are not hospitalized or those who do not meet the criteria for heart transplantation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, safe, and effective option for managing severe heart failure in children, potentially improving their chances of survival and quality of life.

How similar studies have performed: While the use of left ventricular assist devices in adults has shown success, this specific application in pediatric patients is novel and aims to address significant gaps in current treatment options.

Where this research is happening

Wilmington, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.