Using a medication to help asthma patients with frequent flare-ups
Official title: A Selective Serotonin Reuptake Inhibitor for Asthma Patients with Frequent Exacerbations
Funded at Ut Southwestern Medical Center · NIH-10806899 · Data updated 2026-11-12
This study is looking at whether a type of medication called SSRIs can help adults with asthma feel better and need less steroid treatment, especially for those who often have asthma flare-ups, including women and African Americans who are more affected by asthma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $790,698 |
| NIH project number | 1R61HL167909-01A1 |
| Project ID | NIH-10806899 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who suffer from asthma and experience frequent exacerbations despite current treatments.
✕Less likely to help
Patients with well-controlled asthma or those who do not experience frequent exacerbations may not benefit from this research.
What this research studies
This research investigates the effects of selective serotonin reuptake inhibitors (SSRIs) on asthma control in adults who experience frequent exacerbations. The study aims to determine if SSRIs can improve asthma symptoms and reduce the need for corticosteroids in patients, regardless of their depression status. Participants will be monitored for changes in their asthma control and exacerbation rates over the course of the study. The research is particularly focused on adults, especially women and African Americans, who are disproportionately affected by asthma.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that significantly improve asthma control for patients with frequent exacerbations.
How similar studies have gone: Previous studies have shown promising results with SSRIs in improving asthma control, suggesting that this approach may be effective.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Brown, E Sherwood — Ut Southwestern Medical Center
- Study coordinator: Brown, E Sherwood
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.