Using a laser system to prepare bone and tooth tissue samples for analysis
Official title: Acquisition of a laser microtomy system for hard tissue histology
Funded at Rush University Medical Center · NIH-10852356 · Data updated 2026-11-12
This study is testing a new laser tool that helps scientists prepare tiny slices of hard tissues like bones and teeth, making it easier to learn about bone growth and related health issues, which could lead to better treatments for people with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | May 15, 2024 |
| Project end | May 14, 2026 |
| Funding year | 2024 |
| Award (this year) | $462,680 |
| NIH project number | 1S10OD036245-01 |
| Project ID | NIH-10852356 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals suffering from bone disorders, osteoarthritis, or those requiring dental reconstruction.
✕Less likely to help
Patients with soft tissue conditions or those not affected by bone-related issues may not receive any benefit from this research.
What this research studies
This research focuses on acquiring a specialized laser microtomy system called TissueSurgeon, which allows for the preparation of histology slides from hard tissues like bone and teeth without the need for decalcification. This innovative equipment will enable researchers to create ultra-thin sections of these tissues, facilitating advanced studies in bone growth, regeneration, and related diseases. The system enhances the accuracy and efficiency of histological analysis, which is crucial for understanding various bone disorders and improving treatment methods. By utilizing this technology, researchers aim to advance the field of tissue engineering and dental reconstruction.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for patients with bone diseases and disorders.
How similar studies have gone: Other research has shown success with similar laser microtomy techniques, indicating a promising avenue for advancing histological analysis.
Where this research is happening
-
Rush University Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Sumner, D Rick — Rush University Medical Center
- Study coordinator: Sumner, D Rick
Related research
Other NIH-funded projects on the same topics.
-
Understanding Fragile X Syndrome: How it progresses and affects daily life
A long-term study using existing Fragile X data to map how the condition changes over time in children and young adults, including how autism, race, and location influence outcomes.
-
Understanding how brain resilience and multiple brain pathologies influence aging and Alzheimer's disease
A long-term study follows older adults to learn how resilience to brain changes helps reduce dementia risk and what biological factors are linked to better cognitive aging.
-
Mexican Teachers Cohort Study: Genetics and Cognitive Function
A large study using genetic data from Mexican teachers to discover genetic factors linked to memory and thinking in older adults.
-
Genetics and Cognitive Function in Mexican Teachers Cohort for Alzheimer’s Dementia
This grant funds a large study to find genetic factors linked to memory and thinking in Mexican teachers, with the goal of improving understanding of Alzheimer’s-related dementia.
-
Menstrual cups for economically vulnerable women to improve vaginal health and reduce sexually transmitted infections
A single-arm study will test whether using menstrual cups helps economically vulnerable women reduce bacterial vaginosis and sexually transmitted infections by promoting safer menstrual practices.
-
Gut-Brain Axis in Parkinson’s Disease: biomarkers and procedures to track progression
A patient-focused program to study how gut health and the brain interact in Parkinson’s disease using biomarkers and clinical procedures.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.