Using a laser system to prepare bone and tooth tissue samples for analysis

Acquisition of a laser microtomy system for hard tissue histology

['FUNDING_OTHER'] · RUSH UNIVERSITY MEDICAL CENTER · NIH-10852356

This study is testing a new laser tool that helps scientists prepare tiny slices of hard tissues like bones and teeth, making it easier to learn about bone growth and related health issues, which could lead to better treatments for people with these conditions.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRUSH UNIVERSITY MEDICAL CENTER (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10852356 on ClinicalTrials.gov

What this research studies

This research focuses on acquiring a specialized laser microtomy system called TissueSurgeon, which allows for the preparation of histology slides from hard tissues like bone and teeth without the need for decalcification. This innovative equipment will enable researchers to create ultra-thin sections of these tissues, facilitating advanced studies in bone growth, regeneration, and related diseases. The system enhances the accuracy and efficiency of histological analysis, which is crucial for understanding various bone disorders and improving treatment methods. By utilizing this technology, researchers aim to advance the field of tissue engineering and dental reconstruction.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals suffering from bone disorders, osteoarthritis, or those requiring dental reconstruction.

Not a fit: Patients with soft tissue conditions or those not affected by bone-related issues may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for patients with bone diseases and disorders.

How similar studies have performed: Other research has shown success with similar laser microtomy techniques, indicating a promising avenue for advancing histological analysis.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: bone disorder, Bone Diseases

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.