Using a ketogenic diet to improve symptoms of Alzheimer's disease
Validation and Mechanistic Interrogation of Metabolism Targeting for AD
This study is looking at whether following a ketogenic diet can help improve brain health and memory in people with Alzheimer's disease, and you'll be randomly placed on either this diet or a different healthy eating plan for three months to see how it affects your thinking and overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10766114 on NIH RePORTER |
What this research studies
This research investigates whether a ketogenic diet can positively impact patients with Alzheimer's disease by altering brain energy metabolism. Participants will be randomly assigned to either a ketogenic diet or a Therapeutic Lifestyles Changes diet for three months. The study will assess changes in cognitive function and other health markers before and after the diet interventions. By analyzing the effects of these diets, researchers aim to understand how dietary changes can influence Alzheimer's symptoms and overall brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease who are willing to participate in dietary changes.
Not a fit: Patients with other forms of dementia or those who are unable to adhere to dietary restrictions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a dietary intervention that improves cognitive function and quality of life for Alzheimer's patients.
How similar studies have performed: Previous research has shown promising results with dietary interventions in Alzheimer's disease, suggesting potential for success in this approach.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Swerdlow, Russell H. — University of Kansas Medical Center
- Study coordinator: Swerdlow, Russell H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.