Using a ketogenic diet to help recovery after spinal cord injuries

Evaluation of a Ketogenic Diet for Improvement of Neurological Recovery in Individuals with Acute Spinal Cord Injury

NIH-funded research Ohio State University · NIH-10754456

This study is looking at how a high-fat, low-carb ketogenic diet might help people recover better after a spinal cord injury by reducing inflammation and protecting nerve cells, and it’s for anyone who has recently experienced this type of injury.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project IDNIH-10754456 on NIH RePORTER

What this research studies

This research investigates the effects of a ketogenic diet, which is high in fats and low in carbohydrates, on neurological recovery in individuals who have suffered acute spinal cord injuries. The study aims to understand how this diet can provide neuroprotective benefits by reducing inflammation and cell death in the spinal cord. Participants will follow the ketogenic diet for five weeks, and their motor functions will be assessed to determine any improvements compared to those on a standard hospital diet. The research builds on previous findings that suggest dietary changes can enhance recovery outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced an acute spinal cord injury and are willing to follow a ketogenic diet.

Not a fit: Patients with chronic spinal cord injuries or those who cannot adhere to dietary changes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary interventions that significantly improve recovery and quality of life for patients with spinal cord injuries.

How similar studies have performed: Previous studies have shown promising results with dietary interventions in animal models, but this approach in humans is still being explored.

Where this research is happening

Columbus, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.