Using a glucagon pump to prevent severe low blood sugar after weight loss surgery
Glucagon Pump Therapy for Post-Bariatric Hypoglycemia: Merging Physiology and Engineering
This study is looking at a new device that automatically gives glucagon to help people who have had weight loss surgery and might experience dangerously low blood sugar levels, making it easier for them to manage their condition safely.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Joslin Diabetes Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10932425 on NIH RePORTER |
What this research studies
This research investigates the use of a closed-loop glucagon pump system to manage severe hypoglycemia that can occur after bariatric surgery. It aims to develop a technology that automatically detects low blood sugar levels and delivers glucagon to prevent dangerous drops in glucose. The study will involve patients who have undergone gastric bypass or sleeve gastrectomy and may experience post-bariatric hypoglycemia. Participants will be monitored in a clinical setting to assess the effectiveness and safety of this innovative therapy.
Who could benefit from this research
Good fit: Ideal candidates are adults who have had bariatric surgery and experience episodes of severe hypoglycemia.
Not a fit: Patients who have not undergone bariatric surgery or do not experience hypoglycemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the management of hypoglycemia for patients who have undergone bariatric surgery, enhancing their quality of life and safety.
How similar studies have performed: Previous studies have shown promise in using closed-loop systems for managing blood sugar levels, indicating potential success for this approach.
Where this research is happening
Boston, United States
- Joslin Diabetes Center — Boston, United States (Active)
Researchers
- Principal investigator: Patti, Mary E — Joslin Diabetes Center
- Study coordinator: Patti, Mary E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.