Using a blood test and imaging to detect germ cell tumors earlier and more accurately.

Who could benefit from this research

What this research studies

This research investigates the use of a specific biomarker, miR371a-3p, in conjunction with conventional radiology imaging to improve the detection of active germ cell malignancies. By analyzing blood samples and imaging data from patients enrolled in ongoing clinical trials, the study aims to develop a predictive model that can identify tumor relapse more accurately and at an earlier stage. The approach focuses on patients with early-stage germ cell tumors who are under surveillance, leveraging existing clinical data to enhance diagnostic capabilities.

Why it matters

Where this research is happening

• Provincial Health Services Authority
  Vancouver, Canada Active

Researchers

• Principal investigator: Nappi, Lucia — Provincial Health Services Authority
• Study coordinator: Nappi, Lucia

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.