Using a blood test and imaging to detect germ cell tumors earlier and more accurately.
Integrating investigational miR371a-3p with conventional radiology imaging for earlier and more precise detection of active germ cell malignancy: A BCC/SWOG/S1823 secondary use of data collaboration.
['FUNDING_R37'] · PROVINCIAL HEALTH SERVICES AUTHORITY · NIH-10820385
This study is looking at a special blood test to help doctors find out if germ cell tumors are coming back in patients who are being watched closely, so they can catch any problems earlier and improve treatment.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PROVINCIAL HEALTH SERVICES AUTHORITY (nih funded) |
| Locations | 1 site (VANCOUVER, CANADA) |
| Trial ID | NIH-10820385 on ClinicalTrials.gov |
What this research studies
This research investigates the use of a specific biomarker, miR371a-3p, in conjunction with conventional radiology imaging to improve the detection of active germ cell malignancies. By analyzing blood samples and imaging data from patients enrolled in ongoing clinical trials, the study aims to develop a predictive model that can identify tumor relapse more accurately and at an earlier stage. The approach focuses on patients with early-stage germ cell tumors who are under surveillance, leveraging existing clinical data to enhance diagnostic capabilities.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with early-stage germ cell tumors who are currently under surveillance.
Not a fit: Patients with advanced-stage germ cell tumors or those not undergoing surveillance may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more precise detection of germ cell tumors, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using biomarkers for cancer detection, suggesting that this approach could be effective.
Where this research is happening
VANCOUVER, CANADA
- PROVINCIAL HEALTH SERVICES AUTHORITY — VANCOUVER, CANADA (ACTIVE)
Researchers
- Principal investigator: NAPPI, LUCIA — PROVINCIAL HEALTH SERVICES AUTHORITY
- Study coordinator: NAPPI, LUCIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers