Using 3D printing to deliver engineered extracellular vesicles for tissue repair
3D Encapsulation, Bioprinting and Controlled Delivery of Functionally Engineered EVs (FEEs)
This study is exploring a new way to help heal damaged tissues by using 3D printing to deliver tiny particles that can reduce inflammation and boost healing, which could be really helpful for patients dealing with conditions that slow down recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11098587 on NIH RePORTER |
What this research studies
This research focuses on improving tissue repair by using 3D printing technology to deliver specially engineered extracellular vesicles (EVs) that can modulate inflammation and promote regeneration. The approach involves creating 3D printed scaffolds that can release these EVs in a controlled manner, targeting specific tissues and pathways. By harnessing the natural properties of mesenchymal stem cell-derived EVs, the research aims to enhance the healing process in conditions where inflammation disrupts normal tissue repair. Patients may benefit from this innovative method that combines advanced bioprinting techniques with regenerative medicine.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with chronic injuries or conditions that impair tissue repair, particularly those involving bone regeneration.
Not a fit: Patients with acute injuries or those who do not have conditions affecting tissue regeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for tissue injuries and diseases by improving the body's natural healing processes.
How similar studies have performed: Previous research has shown promise in using engineered extracellular vesicles for tissue repair, but this specific approach utilizing 3D printing is relatively novel.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Ravindran, Sriram — University of Illinois at Chicago
- Study coordinator: Ravindran, Sriram
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.