Using 3D-printed scaffolds to help heal bone and soft tissue injuries
Multi-Tissue Craniofacial Engineering using 3D-BMP9-Notch-Synergized Graphene Citrate Composite Scaffolds
This study is exploring a new way to help heal serious bone and skin injuries by using special 3D-printed structures filled with stem cells from urine, aiming to create better treatments for people with major facial injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11018525 on NIH RePORTER |
What this research studies
This research investigates the use of advanced 3D-printed scaffolds combined with stem cells to regenerate bone and soft tissue, particularly in cases of severe injuries. The approach involves using human adult-derived urine stem cells that are stimulated to differentiate into bone and skin cells, which are then delivered within customized scaffolds designed to fit specific defects. The goal is to develop effective treatments for critical-sized craniofacial defects, which could be particularly beneficial for patients with traumatic injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with critical-sized craniofacial defects, including those resulting from trauma or battlefield injuries.
Not a fit: Patients with non-critical injuries or those who do not have craniofacial defects may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that significantly improve healing outcomes for patients with severe craniofacial injuries.
How similar studies have performed: Previous research has shown promise in using 3D-printed scaffolds and stem cells for tissue regeneration, indicating a potential for success in this novel approach.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Reid, Russell R. — University of Chicago
- Study coordinator: Reid, Russell R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.