USC Norris Translational and Clinical Sciences Program
Translational and Clinical Sciences
['FUNDING_P30'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11238018
The USC Norris program develops new cancer drugs, runs early-phase and investigator-led clinical trials, and creates blood tests to help adults with cancers common in the Los Angeles area.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11238018 on ClinicalTrials.gov |
What this research studies
At USC Norris, a multidisciplinary team looks for new molecular targets and develops therapies aimed at cancers important to their local community. They design and run early-phase and investigator-initiated clinical trials to test those treatments in adults. The program also develops and validates circulating biomarkers and diagnostic tests to track cancer evolution and treatment response. Projects include targeted drug development (for example, Artemis inhibitors in leukemia) and novel immunotherapy combination strategies informed by laboratory findings.
Who could benefit from this research
Good fit: Adults (age 21+) with cancer—particularly patients treated at or able to travel to USC Norris and those with cancers prioritized in the center's catchment area—would be most likely to qualify for related trials or biomarker studies.
Not a fit: People without cancer, pediatric patients, or adults who live too far to access USC Norris or who do not meet trial eligibility criteria are unlikely to directly benefit from this program.
Why it matters
Potential benefit: If successful, this work could produce new targeted treatments, better combination immunotherapies, and blood-based tests that help guide care and monitor response.
How similar studies have performed: Some elements build on prior successes—combining epigenetic agents with immunotherapy and using circulating biomarkers have shown promise—while specific targets and combinations in this program remain experimental.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ITO, FUMITO — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: ITO, FUMITO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Center Support Grant, Cancer Treatment, Cancers, Center for Cancer Research