Upper Midwest emergency care hub
SIREN - Upper Midwest Hub
This project builds a regional hub to speed up and run emergency treatment trials for people with severe, time-sensitive illnesses or injuries in the Upper Midwest.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11307021 on NIH RePORTER |
What this research studies
The hub connects hospitals, EMS teams, and clinics across the Upper Midwest to run more timely clinical trials for emergency conditions. It supports enrolling patients who arrive critically ill or injured, including using prehospital procedures and special exception-from-consent (EFIC) approaches when immediate consent is not possible. The program focuses on expanding reach into rural areas and improving tele-research capacity while training clinicians to run pragmatic and ethical emergency trials. That means more opportunities to test and bring better treatments for stroke, cardiac arrest, major trauma, severe COVID, and other urgent conditions.
Who could benefit from this research
Good fit: People treated by EMS or who arrive at participating emergency departments with severe, time-sensitive conditions (for example stroke, cardiac arrest, major trauma, or severe COVID) at sites in the Upper Midwest are the ideal candidates.
Not a fit: Patients with stable, non-urgent conditions or those who do not receive care at participating sites are unlikely to be enrolled or directly benefit from this hub.
Why it matters
Potential benefit: If successful, the hub could lead to faster testing and wider use of better emergency treatments and more treatment options for patients.
How similar studies have performed: Previous SIREN activities and other multicenter emergency research networks have successfully enrolled large numbers of critically ill patients and informed improvements in emergency care, so this continues an established approach.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Miner, James R. — University of Minnesota
- Study coordinator: Miner, James R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.