Upgrading a detector for advanced X-ray imaging in structural biology
Official title: An upgrade of the area detector for the FMX beamline at NSLS-II
Funded at State University New York Stony Brook · NIH-11102181 · Data updated 2026-11-12
This study is working on upgrading a special X-ray detector to help scientists take better and faster pictures of tiny biological crystals, which can lead to new medicines and a better understanding of diseases that affect patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | April 15, 2025 |
| Project end | April 14, 2026 |
| Funding year | 2025 |
| Award (this year) | $1,964,800 |
| NIH project number | 1S10OD038241-01 |
| Project ID | NIH-11102181 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that require novel drug therapies or those involved in clinical trials for new medications.
✕Less likely to help
Patients with conditions that do not involve drug therapies or structural biology may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the X-ray area detector used at the Frontier Microfocusing Macromolecular Crystallography beamline. By replacing the existing detector with a more advanced model, the project aims to significantly improve the speed and quality of data collection from biological crystals. This upgrade will allow researchers to obtain higher resolution images and analyze more crystals efficiently, which is crucial for drug discovery and understanding biological structures. Patients may benefit indirectly through advancements in drug development and improved understanding of diseases.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective drug development processes, ultimately benefiting patients with various medical conditions.
How similar studies have gone: Similar upgrades in X-ray detection technology have shown success in enhancing data collection in structural biology, indicating a promising approach.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Liu, Qun — State University New York Stony Brook
- Study coordinator: Liu, Qun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.