University of Cape Town HIV and TB Clinical Trials Unit
Official title: HIV/AIDS Clinical Trials Units University of Cape Town CTU 2020 to 2027
Funded at University of Cape Town · NIH-11234234 · Data updated 2026-11-12
This program runs clinical trials of new and improved HIV and tuberculosis treatments and prevention methods for people living in and around Cape Town, South Africa.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cape Town NIH-funded |
| Lab location | 1 site (Rondebosch, South Africa) |
| Project start | April 1, 2007 |
| Project end | November 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $2,748,593 |
| NIH project number | 5UM1AI069519-20 |
| Project ID | NIH-11234234 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people living with HIV or tuberculosis, or those at elevated risk of these infections in the Cape Town area who meet specific trial eligibility criteria.
✕Less likely to help
People who live far from Cape Town, who do not meet trial eligibility rules, or whose condition is unrelated to HIV/TB are unlikely to directly benefit from these specific trials.
What this research studies
You would be connecting with a clinical trials unit based at the Desmond Tutu HIV Centre that runs studies in communities around Cape Town where HIV and TB are common. The unit supports six local research sites and offers treatment and prevention trials for HIV, tuberculosis, and related sexually transmitted infections. Trials involve regular clinic visits, medical exams, and may include blood or other sample collection to track health and study how treatments work. Joining a trial could mean closer medical monitoring and access to new therapies under careful supervision.
Why it matters
Potential benefit: If successful, this work could bring better treatments and prevention options for people with HIV and tuberculosis in southern Africa and beyond.
How similar studies have gone: Many prior clinical trials in HIV and TB have led to effective medicines and prevention tools, and this program builds on that well-established track record.
Where this research is happening
-
University of Cape Town
Rondebosch, South Africa Active
Researchers
- Principal investigator: Bekker, Linda-Gail Gail — University of Cape Town
- Study coordinator: Bekker, Linda-Gail Gail
Related research
Other NIH-funded projects on the same topics.
-
An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
-
FIOCRUZ HIV/AIDS Clinical Trials Unit: advancing HIV prevention and treatment in Brazil
A Brazilian clinical trials unit led by Dr. Beatriz Grinsztejn is testing and speeding up new HIV prevention and treatment strategies to help people living with HIV/AIDS and those at risk.
-
Breeding colony expansion to support HIV/AIDS research with rhesus macaques
A funding opportunity to expand a specialized Rhesus macaque breeding population to support HIV/AIDS research at Tulane’s primate facility.
-
HIV Resilience Observatory in a rhesus macaque colony expansion
A program to build a rhesus macaque breeding colony and use AI-powered monitoring to study why some HIV/AIDS outcomes differ among individuals with similar backgrounds.
-
Indoor-Outdoor Housing Expansion to Support HIV/AIDS-Related Research
A HIV-focused project at a primate research center will use new indoor/outdoor housing and AI-assisted monitoring to study why people with similar backgrounds can have very different HIV outcomes.
-
Hearing changes in people with HIV and in people without HIV in Tanzania
This project follows people living with HIV and similar individuals in Tanzania to see how hearing and brain function relate over time and whether hearing tests can help predict cognitive changes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.