NIH-funded research R01 grant

UnityPhilly App to Help Reversal of Overdoses in Philadelphia

Official title: UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and Sustainability

Funded at Drexel University · NIH-11624824 · Data updated 2026-11-12

A citywide smartphone app helps bystanders link with nearby people who can give naloxone during opioid overdoses in Philadelphia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDrexel University
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 30, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$166,514
NIH project number3R01DA055851-04S1
Project IDNIH-11624824 on NIH RePORTER

Who could benefit from this research

Could help

People in Philadelphia who are at risk of opioid overdose or who may witness overdoses and be willing to participate in a study of the UnityPhilly app.

Less likely to help

Individuals not involved in overdose events or not using the app may not directly benefit.

What this research studies

This project expands a previously tested app to be easy to use, widely deployable, and sustainable across Philadelphia to reduce overdose deaths. By following up on a successful feasibility study, the research will study diverse groups of app users (up to about 450 participants) to understand how the app works in real-world settings and what makes it work best. The study will gather data on how quickly responders are notified, how often naloxone is used, and how the community responds in different neighborhoods, with a focus on practicality and long-term adoption. The goal is to confirm that the app can be scaled citywide and maintained over time to save lives. Participants likely include individuals at risk of overdose, bystanders, and community organizations engaged in overdose response.

Why it matters

Potential benefit: If successful, the app could reduce overdose deaths by speeding life-saving naloxone delivery and strengthening community response in Philadelphia.

How similar studies have gone: Prior feasibility work supports that similar app-based approaches can aid overdose reversal in real-world settings.

Where this research is happening

  • Drexel University
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Lankenau, Stephen E — Drexel University
  • Study coordinator: Lankenau, Stephen E

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.