Understanding Zinc and Genes in Prediabetes

Clinical and Nutrigenetic Assessment of Zinc in Patients with Prediabetes

NIH-funded research University of Maryland Baltimore · NIH-11112485

This research explores how zinc and your genes might work together to affect prediabetes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11112485 on NIH RePORTER

What this research studies

Many people have prediabetes, a condition that can lead to serious health problems like type 2 diabetes and heart disease. Currently, lifestyle changes are the main way to manage prediabetes, but we need more options to slow or prevent its progression. This project looks at how zinc, an important mineral, influences insulin and blood sugar in the body. We also want to understand if certain genetic differences affect how zinc works in your body. By studying these factors, we hope to find new ways to help people with prediabetes.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals diagnosed with prediabetes.

Not a fit: Patients who do not have prediabetes or are already managing established type 2 diabetes may not directly benefit from this specific research focus.

Why it matters

Potential benefit: If successful, this work could lead to new strategies, possibly involving zinc supplementation, to slow or prevent the progression of prediabetes to type 2 diabetes.

How similar studies have performed: Previous investigations, primarily in type 2 diabetes patients, have shown that zinc supplementation can have positive effects on blood sugar levels.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusCardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.