Understanding Wolbachia Bacteria to Fight Insect-Spread Diseases

The evolutionary genetics and genomics of Wolbachia effects on host physiology

NIH-funded research University of Montana · NIH-11128720

This research helps us understand how tiny Wolbachia bacteria affect insects like mosquitoes, which could lead to new ways to prevent diseases such as dengue.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Montana NIH-funded
Lab location1 site (Missoula, United States)
Project IDNIH-11128720 on NIH RePORTER

What this research studies

Many animals, including insects, carry tiny microbes called endosymbionts inside their cells, and these microbes can greatly change the insect's biology. This project focuses on Wolbachia bacteria, which are very common in insects and can influence their health and ability to reproduce. By learning how Wolbachia spreads and affects insects, we hope to improve methods that use these bacteria to control mosquito populations. This could help reduce the spread of diseases like dengue fever to people.

Who could benefit from this research

Good fit: This foundational research focuses on insect biology and does not involve direct patient participation.

Not a fit: Patients would not receive direct medical benefit from this specific research, as it is focused on insect populations.

Why it matters

Potential benefit: If successful, this work could lead to more effective strategies for controlling disease-carrying insects, ultimately protecting people from illnesses like dengue.

How similar studies have performed: Other efforts are already attempting to use Wolbachia for biocontrol, and this research aims to improve the effectiveness of these existing approaches.

Where this research is happening

Missoula, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.