NIH-funded research R01 grant

Understanding why U.S. cardiovascular disease deaths are not decreasing

Official title: Identifying the Causes of the Stagnation in National U.S. Cardiovascular Disease Mortality

Funded at University of Texas Med Br Galveston · NIH-11012786 · Data updated 2026-11-12

This study is looking into why the number of people dying from heart disease in the U.S. hasn't been going down since 2010, and it's for anyone interested in understanding how things like obesity, smoking, and economic challenges might be affecting heart health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Med Br Galveston
NIH-funded
Lab location1 site (Galveston, United States)
Project startFebruary 15, 2023
Project endJanuary 31, 2027
Funding year2025
Award (this year)$334,284
NIH project number5R01AG075208-03
Project IDNIH-11012786 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit include individuals at risk for cardiovascular disease, particularly those affected by obesity, smoking, or socio-economic challenges.

Less likely to help

Patients with no history of cardiovascular disease risk factors or those who are not affected by obesity or smoking may not receive direct benefits from this research.

What this research studies

This research investigates the reasons behind the stagnation in cardiovascular disease (CVD) mortality rates in the U.S. since 2010. The team will explore various factors, including rising obesity rates, changes in smoking habits, and socio-economic vulnerabilities that may contribute to this issue. By analyzing historical data and trends, they aim to identify the key drivers of CVD mortality stagnation and provide insights into potential interventions. Patients may benefit from improved understanding and strategies to address these critical health issues.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that reduce cardiovascular disease mortality and improve overall public health.

How similar studies have gone: Previous research has successfully identified factors contributing to cardiovascular disease trends, suggesting that this approach may yield valuable insights.

Where this research is happening

  • University of Texas Med Br Galveston
    Galveston, United States
    Active

Researchers

  • Principal investigator: Mehta, Neil — University of Texas Med Br Galveston
  • Study coordinator: Mehta, Neil

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.