NIH-funded research R01 grant

Understanding why some young people develop chronic musculoskeletal pain

Official title: Identifying risk for transition from acute to chronic musculoskeletal pain in youth

Funded at Oregon Health & Science University · NIH-10455657 · Data updated 2026-11-12

This study is looking at why some young people aged 12 to 20 develop long-lasting pain after having short-term pain, and it aims to find out how things like emotions and behaviors play a role, so we can help those who might be at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startSeptember 1, 2018
Project endJuly 31, 2025
Funding year2022
Award (this year)$541,050
NIH project number5R01AR073186-05
Project IDNIH-10455657 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are youth aged 12 to 20 who are experiencing acute musculoskeletal pain.

Less likely to help

Patients who do not have musculoskeletal pain or are outside the age range of 12 to 20 may not benefit from this research.

What this research studies

This research investigates the factors that contribute to the transition from acute to chronic musculoskeletal pain in youth aged 12 to 20. It focuses on understanding how pain modulation, psychosocial factors, and behavioral vulnerabilities influence this transition. By studying these mechanisms, the research aims to identify at-risk individuals and develop targeted interventions. Participants may undergo assessments to evaluate their pain experiences and related psychosocial factors.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for chronic pain in young people.

How similar studies have gone: Previous research has shown success in understanding pain modulation and its impact on chronic pain, indicating that this approach has potential for meaningful insights.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Lewandowski Holley, Amy S — Oregon Health & Science University
  • Study coordinator: Lewandowski Holley, Amy S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.