Understanding why some women experience persistent or early recurring bacterial vaginosis
Official title: Factors associated with Refractory and Early Recurrent Bacterial Vaginosis
Funded at Johns Hopkins University · NIH-11019826 · Data updated 2026-11-12
This study is looking at what causes some women to keep getting bacterial vaginosis (BV) or to have it come back soon after treatment, so we can find better ways to help those who might need stronger treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | February 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $791,678 |
| NIH project number | 5R01AI182384-02 |
| Project ID | NIH-11019826 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cis-gender women who have experienced recurrent bacterial vaginosis or have not responded well to standard treatments.
✕Less likely to help
Patients who have never experienced bacterial vaginosis or those with other unrelated vaginal conditions may not benefit from this research.
What this research studies
This research investigates the factors that contribute to persistent or early recurring bacterial vaginosis (BV) in women. By analyzing the vaginal microbiota and environmental conditions at the time of diagnosis, the study aims to identify specific characteristics that predict poor treatment outcomes. The goal is to develop clinical biomarkers that can help healthcare providers determine which patients may require more aggressive treatment options. This approach could lead to more personalized care for women suffering from BV.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for women with bacterial vaginosis, reducing recurrence rates and associated health risks.
How similar studies have gone: Previous research has shown that understanding the vaginal microbiome can lead to better treatment outcomes for bacterial vaginosis, suggesting that this approach has potential for success.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Tuddenham, Susan Anne — Johns Hopkins University
- Study coordinator: Tuddenham, Susan Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.