Understanding why some racial and ethnic groups have different risks for a blood condition called MGUS
Determinants of the racial/ethnic disparity in MGUS risk: An epidemiologic study in 4 cohorts
This study is looking at why some racial and ethnic groups are more likely to develop a condition called MGUS, and it’s for people with MGUS and those without it, as researchers want to understand how things like health habits and infections might play a role in these differences.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10914033 on NIH RePORTER |
What this research studies
This research investigates the reasons behind the differences in risk for monoclonal gammopathy of undetermined significance (MGUS) among various racial and ethnic groups. By examining data from four diverse cohorts, the study aims to identify factors such as plasma cell growth, chronic infections, and lifestyle influences that may contribute to these disparities. Participants will include individuals with MGUS and matched controls, allowing researchers to analyze and compare their health data. The findings could provide insights into the underlying causes of these disparities and inform future prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include Black, Non-Latino White, Latino, and Asian individuals who are either diagnosed with MGUS or are part of the matched control group.
Not a fit: Patients who do not belong to the specified racial or ethnic groups or those without MGUS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention of MGUS and multiple myeloma, particularly in high-risk populations.
How similar studies have performed: Previous research has indicated that understanding racial and ethnic disparities in health conditions can lead to significant advancements in treatment and prevention strategies.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Cozen, Wendy — University of California-Irvine
- Study coordinator: Cozen, Wendy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.