Understanding why some people with type 1 diabetes don't recognize low blood sugar
Elucidating the heterogeneity of impaired awareness of hypoglycaemia in type 1 diabetes
This study is looking into why some people with type 1 diabetes don’t notice when their blood sugar is low and aims to create new ways to measure this awareness, especially for those using advanced insulin delivery systems, to help improve education and management for better health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Leicester NIH-funded |
| Lab location | 1 site (Leicester, United Kingdom) |
| Project ID | NIH-11084309 on NIH RePORTER |
What this research studies
This research investigates the reasons behind impaired awareness of hypoglycemia (IAH) in individuals with type 1 diabetes. It aims to develop and validate new tools to objectively measure changes in awareness of low blood sugar levels, particularly in those using hybrid closed loop insulin delivery systems. The study will involve multiple sub-studies that assess physiological responses to low blood sugar and the effectiveness of advanced technology in restoring awareness. By understanding these factors, the research seeks to improve patient education and management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with type 1 diabetes who experience impaired awareness of hypoglycemia.
Not a fit: Patients who do not have type 1 diabetes or those who do not experience issues with hypoglycemia awareness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of low blood sugar awareness in patients with type 1 diabetes, reducing the risk of severe hypoglycemic events.
How similar studies have performed: Previous research has shown promise in using technology to improve awareness of hypoglycemia, but this approach aims to refine and validate new assessment tools, making it a novel endeavor.
Where this research is happening
Leicester, United Kingdom
- University of Leicester — Leicester, United Kingdom (Active)
Researchers
- Principal investigator: Choudhary, Pratik — University of Leicester
- Study coordinator: Choudhary, Pratik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.