Understanding why some kids develop Type 2 diabetes as they grow
Official title: Metabolic, behavioral and social determinants of youth-onset T2D
Funded at Albert Einstein College of Medicine · NIH-11519707 · Data updated 2026-11-12
This project follows youth at risk for Type 2 diabetes to understand how puberty, obesity, and social factors influence who develops the condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | April 1, 2026 |
| Project end | January 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $89,999 |
| NIH project number | 3U01DK134988-04S1 |
| Project ID | NIH-11519707 on NIH RePORTER |
Who could benefit from this research
✓Could help
Youth aged roughly 8–15 who are at risk for developing Type 2 diabetes, especially those with obesity or insulin resistance.
✕Less likely to help
Youth without obesity or insulin resistance may have limited direct benefit from this study.
What this research studies
Young people who are at risk for Type 2 diabetes will be followed over time to see how changing hormones during puberty, body weight, behaviors, and life circumstances affect insulin and beta-cell function. The study will look at differences between girls and boys, and across urban and rural settings, to identify when and why risk escalates. Researchers will track factors like diet, activity, stress, and access to care to map how these elements relate to glucose control from normal to prediabetes and diabetes.
Why it matters
Potential benefit: Findings could guide personalized prevention strategies for youth at risk, potentially slowing or preventing YO-T2D.
How similar studies have gone: Previous work has shown that puberty and obesity interact with diabetes risk, but this study aims to clarify pathways in diverse youth populations.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Isasi, Carmen R. — Albert Einstein College of Medicine
- Study coordinator: Isasi, Carmen R.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.