Understanding why some adolescents with cerebral palsy improve with treatment while others do not

NEUROPHYSIOLOGY OF RESPONDERS AND NON-RESPONDERS WITH CEREBRAL PALSY

['FUNDING_R01'] · FATHER FLANAGAN'S BOYS' HOME · NIH-10843835

This study is looking at how the brains of teenagers with cerebral palsy work differently when they respond well to walking training compared to those who don’t, so we can create better, personalized treatments to help everyone move more easily.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorFATHER FLANAGAN'S BOYS' HOME (nih funded)
Locations1 site (BOYS TOWN, UNITED STATES)
Trial IDNIH-10843835 on ClinicalTrials.gov

What this research studies

This research investigates the differences in brain function between adolescents with cerebral palsy who respond well to gait training and those who do not. By using advanced brain imaging techniques like magnetoencephalography (MEG) and MRI, the study aims to identify the underlying neurophysiological mechanisms that contribute to these varied treatment outcomes. The goal is to develop more effective, personalized treatment strategies that enhance mobility for all adolescents with cerebral palsy. Patients participating in this research will undergo assessments that help researchers understand their unique responses to therapy.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents diagnosed with cerebral palsy who are undergoing or have undergone gait training.

Not a fit: Patients with cerebral palsy who are not currently receiving gait training or have other unrelated mobility issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment protocols that enhance mobility and quality of life for adolescents with cerebral palsy.

How similar studies have performed: Previous research has shown promising results in understanding treatment responses in similar patient populations, indicating that this approach has the potential for success.

Where this research is happening

BOYS TOWN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Child Development Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.