Understanding why people respond differently to the influenza vaccine
Drivers of individual variation in influenza vaccine response and protection from infection
This study is looking at what affects how well people respond to the flu vaccine, considering things like their vaccination history, immune system, age, and gender, to help make vaccines more effective for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10888291 on NIH RePORTER |
What this research studies
This research investigates the factors that influence how individuals respond to the influenza vaccine, focusing on the immune responses that provide protection against infection. By examining variables such as vaccination history, immune system characteristics, and personal factors like age and sex, the study aims to identify what drives differences in vaccine effectiveness among people. The researchers will use a combination of data analysis and immune response measurements to better understand these variations and improve vaccine development.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who receive the influenza vaccine and may have varying responses based on their immune system characteristics.
Not a fit: Patients who do not receive the influenza vaccine or have conditions that prevent them from participating in vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective influenza vaccines tailored to individual immune responses.
How similar studies have performed: Previous research has shown that understanding immune responses can significantly enhance vaccine effectiveness, indicating that this approach has potential for success.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Cobey, Sarah — University of Chicago
- Study coordinator: Cobey, Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.