Understanding why people regain weight after losing it
Predicting Weight Regain Following Weight Loss Using Physiological Measures of Appetite and Energy Expenditure
This study is looking at why some people gain weight back after losing it, by checking how their bodies change in terms of hunger and energy use, and it's for anyone who has lost weight and wants to understand how to keep it off better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11085069 on NIH RePORTER |
What this research studies
This research investigates the reasons behind weight regain after successful weight loss, focusing on physiological changes in appetite and energy expenditure. Participants will engage in a weight loss program and will be monitored over time to assess how their metabolism and appetite influence their ability to maintain weight loss. The study will involve both individuals who have lost weight and a control group of weight-stable individuals to identify key differences in their physiological responses. By analyzing these factors, the research aims to provide insights into effective strategies for long-term weight management.
Who could benefit from this research
Good fit: Ideal candidates are individuals who are currently overweight and willing to participate in a structured weight loss program.
Not a fit: Patients who are not overweight or those who are unable to commit to a weight loss program may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for maintaining weight loss and preventing weight regain.
How similar studies have performed: Previous research has shown that understanding physiological responses can significantly impact weight management strategies, suggesting this approach has potential for success.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Lowe, Michael R — Drexel University
- Study coordinator: Lowe, Michael R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.