Understanding why Black and White patients experience different rates of heart disease and stroke.

REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction-4 (REGARDS-MI-4)

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-10904966

This study is looking at why Black and White people in the U.S. experience different rates of heart disease and heart failure, focusing on how social factors and racism play a role, and it aims to understand how people bounce back from heart health issues to help improve care for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10904966 on NIH RePORTER

What this research studies

This research investigates the persistent disparities in coronary heart disease (CHD) and heart failure (HF) between Black and White populations in the U.S. It focuses on how social determinants of health, including structural racism, impact these disparities over a person's lifetime. By examining resilience and recovery after acute health events, the study aims to uncover the underlying mechanisms contributing to these health differences. The research will utilize a national sample to provide rigorously adjudicated data on CHD and HF events, which can be used by other investigators as well.

Who could benefit from this research

Good fit: Ideal candidates for this research include Black and White adults who are at risk for or have experienced coronary heart disease or heart failure.

Not a fit: Patients who do not identify as Black or White or those without a history of cardiovascular issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions that reduce heart disease and stroke disparities among different racial groups.

How similar studies have performed: Previous research has shown that addressing social determinants of health can lead to meaningful improvements in health outcomes, suggesting potential success for this approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.