Understanding why bacterial vaginosis keeps coming back and its link to HIV risk
Mechanisms underlying recurrent bacterial vaginosis and HIV risk A Multidisciplinary approach
This study is looking at why bacterial vaginosis keeps coming back in women and how it might increase the risk of HIV and STIs, so if you're a woman aged 18-45 with BV, you can get treatment and help us learn more about what causes it to return and how to prevent it better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10675424 on NIH RePORTER |
What this research studies
This research investigates the reasons behind the recurrence of bacterial vaginosis (BV) in women and its connection to an increased risk of HIV and sexually transmitted infections (STIs). It focuses on how changes in vaginal bacteria affect women's health, particularly looking at the role of hygiene practices, the microbiome, and immune responses. Women aged 18-45 with BV will receive treatment and be monitored over time to understand the factors that contribute to BV recurrence. The study aims to provide insights that could lead to better prevention and treatment strategies for BV and its associated risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are reproductive-age women between 18 and 45 years who are experiencing bacterial vaginosis.
Not a fit: Patients who do not have bacterial vaginosis or are outside the reproductive age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for bacterial vaginosis, reducing the risk of HIV and STIs in women.
How similar studies have performed: Previous research has shown that understanding the microbiome and immune responses can lead to better management of bacterial infections, suggesting potential success for this approach.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Alcaide, Maria Luisa — University of Miami School of Medicine
- Study coordinator: Alcaide, Maria Luisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.