Understanding wheezing in preschool children
Phenotypes and Endotypes of Preschool Wheeze
This study is looking at why some preschool kids between 1 and 5 years old wheeze and how their wheezing might be different, so we can better understand their breathing problems and help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10553158 on NIH RePORTER |
What this research studies
This research investigates the causes and characteristics of wheezing in preschool children aged 12 to 59 months. It aims to identify different phenotypes and endotypes of wheezing to better predict exacerbations and outcomes. By analyzing clinical and biological features, the study seeks to enhance personalized medicine approaches for young children with respiratory issues. The research involves a cohort of 145 preschool children with a history of recurrent wheezing over a 50-week period.
Who could benefit from this research
Good fit: Ideal candidates for this research are preschool children aged 12 to 59 months who have a history of recurrent wheezing.
Not a fit: Patients outside the age range of 12 to 59 months or those without a history of recurrent wheezing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for preschool children experiencing wheezing, ultimately reducing hospital visits and enhancing their quality of life.
How similar studies have performed: Previous research has shown promise in understanding respiratory conditions in children, but this specific approach to stratifying preschool wheezing is relatively novel.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Fitzpatrick, Anne Mentro — Emory University
- Study coordinator: Fitzpatrick, Anne Mentro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.