Understanding what triggers migraine attacks

Measuring Migraine Attack Risks

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10652309

This study is looking at what might cause migraine attacks by tracking 200 people over time to see how things like food, weather, and stress affect their headaches, and it will create a new way to help predict when someone might have a migraine based on their personal triggers.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10652309 on ClinicalTrials.gov

What this research studies

This research investigates the various factors that may trigger migraine attacks in individuals. By observing 200 participants over time, the study aims to identify and quantify the influence of different triggers such as food, weather, and stress on migraine occurrences. A novel measurement system will be developed to provide daily risk scores for migraine attacks based on individual trigger probabilities. This approach seeks to clarify the confusion surrounding migraine triggers and improve forecasting of future attacks.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who experience frequent migraine attacks and are interested in understanding their triggers.

Not a fit: Patients who do not suffer from migraines or have infrequent migraine episodes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help patients better manage their migraines by identifying specific triggers and predicting attack risks.

How similar studies have performed: Previous research has shown promise in identifying migraine triggers, but this approach using information theory is relatively novel and untested.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.