Understanding what makes children susceptible to acute myeloid leukemia

Determinants of susceptibility to pediatric acute myeloid leukemia

['FUNDING_OTHER'] · VAN ANDEL RESEARCH INSTITUTE · NIH-11228686

This study is looking into why some children are more likely to get acute myeloid leukemia (AML) by exploring things like genetics and the environment, and it’s for families affected by this type of cancer to help find better ways to prevent and treat it.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVAN ANDEL RESEARCH INSTITUTE (nih funded)
Locations1 site (GRAND RAPIDS, UNITED STATES)
Trial IDNIH-11228686 on ClinicalTrials.gov

What this research studies

This research investigates the factors that contribute to the risk of developing pediatric acute myeloid leukemia (AML). By analyzing genetic, environmental, and biological determinants, the study aims to identify why some children are more susceptible to this type of cancer. The approach includes collecting data from affected children and their families to better understand the underlying causes. This information could lead to improved prevention strategies and targeted therapies for those at risk.

Who could benefit from this research

Good fit: Ideal candidates for this research include children diagnosed with acute myeloid leukemia and their families.

Not a fit: Patients who do not have acute myeloid leukemia or are not at risk for developing it may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention and treatment options for children at risk of acute myeloid leukemia.

How similar studies have performed: While research on pediatric cancers is ongoing, this specific investigation into the determinants of susceptibility in pediatric AML is relatively novel.

Where this research is happening

GRAND RAPIDS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.