Understanding what makes certain kidney cancers spread
ccRCC Metastatic Competency Determinants
This study is looking at what makes certain kidney tumors, like clear cell renal cell carcinoma, more likely to spread to other parts of the body, so doctors can better understand how to treat patients and predict their outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10885176 on NIH RePORTER |
What this research studies
This research investigates the factors that determine whether invasive kidney tumors, specifically clear cell renal cell carcinoma (ccRCC), can spread to other parts of the body. By analyzing tumor samples and using advanced imaging techniques, the study aims to identify characteristics that indicate a higher risk of metastasis. This information could help doctors better manage and treat patients by predicting which tumors are more likely to spread. The research focuses on understanding the biological mechanisms behind tumor behavior and patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with invasive clear cell renal cell carcinoma who are undergoing treatment or have had surgery.
Not a fit: Patients with non-invasive kidney tumors or those with other types of kidney cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for predicting and managing metastatic kidney cancer, potentially enhancing patient survival rates.
How similar studies have performed: Previous research has shown promise in identifying metastatic determinants in various cancers, suggesting that this approach could yield valuable insights for ccRCC as well.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Malladi, Srinivas — Ut Southwestern Medical Center
- Study coordinator: Malladi, Srinivas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.