Understanding what helps people resist substance use
Using a Genetic Approach to Understand Factors Influencing Resistance to Substance Use
This study is looking at what helps young people say no to drugs and alcohol, focusing on both their genes and their surroundings, so we can find ways to support them in making healthier choices as they grow up.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10873163 on NIH RePORTER |
What this research studies
This research investigates the factors that contribute to an individual's resistance to using psychoactive substances, particularly during adolescence and into early adulthood. By analyzing data from twin studies, the project aims to identify both genetic and environmental influences on resistance to substance use. The researchers will develop indices to measure resistance and explore how modifiable factors can enhance this resistance, potentially leading to better prevention and treatment strategies. Participants will be followed over time to assess long-term substance use behaviors.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who are at risk for substance use or have a family history of substance use disorders.
Not a fit: Patients who are already experiencing severe substance use disorders may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for substance use disorders.
How similar studies have performed: Previous research has shown success in identifying risk factors for substance use, but this approach focusing on resistance is relatively novel.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Prom-Wormley, Elizabeth Chin — Virginia Commonwealth University
- Study coordinator: Prom-Wormley, Elizabeth Chin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.