Understanding what helps adolescents with obesity lose weight and keep it off
Predictors of Weight Loss and Weight Loss Maintenance to Lifestyle Modification Therapy and Pharmacotherapy for Adolescents with Obesity
This study is looking at how certain behaviors and traits can help predict weight loss success in teens with obesity who are trying different treatments, like lifestyle changes or a medication called semaglutide, to find the best ways to support them in reaching and maintaining a healthy weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11098561 on NIH RePORTER |
What this research studies
This research investigates how neurobehavioral characteristics can predict weight loss and maintenance in adolescents with obesity undergoing different treatment approaches. It focuses on two main interventions: intensive lifestyle modification therapy and a combination of lifestyle therapy with a medication called semaglutide. By examining these predictors, the study aims to personalize treatment plans for better outcomes. The research will involve 116 adolescents and will track their progress over time to identify effective strategies for weight management.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are struggling with obesity.
Not a fit: Patients who are not adolescents or those who do not have obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized weight loss treatments for adolescents with obesity.
How similar studies have performed: Previous research has shown promise in using neurobehavioral predictors for weight loss, but this study aims to explore this approach in a novel way with specific interventions.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Gross, Amy C. — University of Minnesota
- Study coordinator: Gross, Amy C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.