Understanding what causes cancer to spread to the liver
Determinants of Liver Metastasis
['FUNDING_P01'] · CEDARS-SINAI MEDICAL CENTER · NIH-10977259
This study is looking into why some cancers, like colon, pancreas, and prostate cancer, spread to the liver more than others, and it’s for anyone affected by these types of cancer who wants to understand how their disease might behave.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CEDARS-SINAI MEDICAL CENTER (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10977259 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms behind liver metastasis, which is when cancer spreads to the liver, a common and serious complication in various cancers. The program aims to identify both shared and unique factors that drive liver metastasis in different types of cancers, such as colon, pancreas, and prostate cancers. By studying the liver's microenvironment and how it interacts with cancer cells, researchers hope to uncover why some tumors are more likely to spread to the liver than others. The approach combines clinical expertise and laboratory models to explore how changes in liver tissue can affect cancer spread.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with colon, pancreas, or prostate cancers who are at risk of liver metastasis.
Not a fit: Patients with cancers that do not typically metastasize to the liver may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating liver metastasis in cancer patients.
How similar studies have performed: Previous research has shown promising results in understanding cancer metastasis, but this program aims to explore novel mechanisms specific to liver metastasis.
Where this research is happening
LOS ANGELES, UNITED STATES
- CEDARS-SINAI MEDICAL CENTER — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LU, SHELLY CHI-LOO — CEDARS-SINAI MEDICAL CENTER
- Study coordinator: LU, SHELLY CHI-LOO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer, Epithelial cancer