NIH-funded research R01 grant

Understanding what causes behavioral symptoms in Alzheimer's disease

Official title: Biological and environmental factors driving behavioral symptoms in Alzheimer's disease

Funded at University of Texas Hlth Sci Ctr Houston · NIH-10888131 · Data updated 2026-11-12

This study is looking at how different personal and environmental factors affect the behaviors of people with Alzheimer's disease, so we can better understand why some experience certain symptoms while others do not, and ultimately improve their care.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 23, 2019
Project endJuly 31, 2025
Funding year2024
Award (this year)$546,583
NIH project number5R01MH121928-07
Project IDNIH-10888131 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Alzheimer's disease who experience behavioral symptoms.

Less likely to help

Patients with Alzheimer's disease who do not exhibit behavioral symptoms may not benefit from this research.

What this research studies

This research investigates how various biological and environmental factors influence the behavioral symptoms experienced by patients with Alzheimer's disease. By examining personal characteristics, environmental stressors, and disease-related factors, the study aims to identify why some patients experience certain symptoms while others do not. The research will utilize daily reports from patients to analyze the variability in symptoms over time, helping to uncover the underlying mechanisms that contribute to these behaviors. Ultimately, the goal is to improve treatment and management strategies for Alzheimer's patients based on these findings.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and management strategies for behavioral symptoms in Alzheimer's disease.

How similar studies have gone: Previous research has shown that understanding the interplay of biological and environmental factors can lead to significant advancements in managing behavioral symptoms in dementia.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Pickering, Carolyn E Ziminski — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Pickering, Carolyn E Ziminski

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.