Understanding what affects the health and lifespan of aging adults with Down syndrome

Predictors of mortality and of healthy survival in a large community-based prospective cohort of aging adults with Down syndrome

NIH-funded research University of Nevada Las Vegas · NIH-10703503

This study is looking at what helps adults with Down syndrome live longer and healthier lives, focusing on heart health and other factors, so we can find ways to improve their care and support.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Nevada Las Vegas NIH-funded
Lab location1 site (Las Vegas, United States)
Project IDNIH-10703503 on NIH RePORTER

What this research studies

This research investigates the factors that influence mortality and healthy aging in adults with Down syndrome. It aims to identify both modifiable and non-modifiable predictors of health outcomes, focusing on cardiovascular risk factors and their impact on longevity. By analyzing data from a large cohort of aging adults with intellectual disabilities, the study seeks to define characteristics of 'healthy survivors' and develop strategies for prevention and early detection of health issues. The ultimate goal is to improve health care resources and lifestyle interventions for this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are aging adults with Down syndrome, particularly those aged 50 and older.

Not a fit: Patients under the age of 50 or those without Down syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and increased life expectancy for adults with Down syndrome.

How similar studies have performed: Previous research has shown success in identifying health predictors in similar populations, but this study aims to provide new insights specific to adults with Down syndrome.

Where this research is happening

Las Vegas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseasescardiovascular disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.