Understanding von Willebrand factor and its role in von Willebrand Disease
Official title: Administrative Core
Funded at Washington University · NIH-11016808 · Data updated 2026-11-12
This study is looking into the genetics of a protein important for blood clotting, called von Willebrand factor, to better understand von Willebrand Disease and hopefully find new and better treatments for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | May 15, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $337,604 |
| NIH project number | 1P01HL173579-01A1 |
| Project ID | NIH-11016808 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with von Willebrand Disease or those with a family history of bleeding disorders.
✕Less likely to help
Patients with other bleeding disorders unrelated to von Willebrand factor may not receive direct benefits from this research.
What this research studies
This research focuses on the genetics and biology of von Willebrand factor (VWF), which is crucial for blood clotting. It aims to understand the mechanisms that cause von Willebrand Disease (VWD) through collaboration among leading scientists from various prestigious institutions. The project will also ensure effective administrative coordination and compliance with research regulations, facilitating the integration of findings across multiple research efforts. Patients may benefit from improved understanding and potential advancements in treatment options for VWD.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and treatment options for patients with von Willebrand Disease.
How similar studies have gone: Previous research on von Willebrand factor has shown promise in understanding bleeding disorders, indicating that this approach is built on a foundation of prior success.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Di Paola, Jorge a — Washington University
- Study coordinator: Di Paola, Jorge a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.