Understanding Voice Problems from Muscle Tension

Sensory Mechanisms in Primary Muscle Tension Dysphonia

['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11140975

This research aims to understand why people with muscle tension dysphonia experience vocal fatigue and discomfort, even when their vocal muscles don't show obvious issues.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUT SOUTHWESTERN MEDICAL CENTER (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-11140975 on ClinicalTrials.gov

What this research studies

Many people experience primary muscle tension dysphonia (pMTD), a voice disorder that makes daily life, work, and overall well-being difficult. While it causes significant hardship, we don't fully understand what causes symptoms like vocal fatigue, discomfort, and difficulty speaking loudly or for long periods. This project explores whether sensory experiences, rather than just muscle tension, play a key role in these symptoms. By looking at how patients perceive their voice and vocal tract, we hope to uncover new insights into the condition.

Who could benefit from this research

Good fit: Ideal candidates for related future studies would be individuals experiencing primary muscle tension dysphonia and its associated symptoms like vocal fatigue and discomfort.

Not a fit: Patients with voice disorders caused by structural issues, neurological conditions, or other known organic problems may not directly benefit from this specific line of research.

Why it matters

Potential benefit: If successful, this work could lead to new ways to diagnose and treat muscle tension dysphonia, offering better relief for patients.

How similar studies have performed: Previous work from the lead researcher's lab has shown that patients with muscle tension dysphonia report different sensory experiences, suggesting this is a promising, yet largely unexplored, area.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.