NIH-funded research R01 grant

Understanding voice problems caused by muscle tension

Official title: Sensory Mechanisms in Primary Muscle Tension Dysphonia

Funded at Ut Southwestern Medical Center · NIH-10931645 · Data updated 2026-11-12

This study is looking into primary muscle tension dysphonia, a voice problem that many people have, to understand how it affects muscle function and sensations, so we can find better ways to help those who struggle with it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center
NIH-funded
Lab location1 site (Dallas, United States)
Project startSeptember 18, 2023
Project endJuly 31, 2028
Funding year2024
Award (this year)$472,448
NIH project number5R01DC021447-02
Project IDNIH-10931645 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing symptoms of primary muscle tension dysphonia, such as vocal fatigue and discomfort while speaking.

Less likely to help

Patients with voice disorders caused by structural or neurological abnormalities may not benefit from this research.

What this research studies

This research investigates primary muscle tension dysphonia (pMTD), a voice disorder affecting millions of people in the U.S. The study aims to explore the underlying sensory mechanisms and muscle function related to this condition, which can lead to vocal fatigue and discomfort. By using validated physiological metrics, researchers will assess the experiences of patients with pMTD compared to healthy individuals. The goal is to better understand the causes of this disorder and improve treatment options for those affected.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for individuals suffering from voice disorders related to muscle tension.

How similar studies have gone: While there have been studies on voice disorders, this research aims to explore a less understood area of muscle tension dysphonia, making it a novel approach.

Where this research is happening

  • Ut Southwestern Medical Center
    Dallas, United States
    Active

Researchers

  • Principal investigator: Shembel, Adrianna — Ut Southwestern Medical Center
  • Study coordinator: Shembel, Adrianna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.