Understanding voice disorders linked to vocal fold muscle loss
Official title: Mechanisms of voice disorders associated with vocal fold atrophy
Funded at New York University School of Medicine · NIH-11001153 · Data updated 2026-11-12
This study is looking into how problems with the muscles in your voice box can lead to voice disorders, and it aims to find out how injuries to the vocal fold area affect these muscles, which could help improve treatments for people with voice issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 15, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $484,006 |
| NIH project number | 5R01DC021453-02 |
| Project ID | NIH-11001153 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing voice disorders related to vocal fold muscle loss, particularly those with a history of laryngeal nerve injury.
✕Less likely to help
Patients with voice disorders not related to muscle atrophy or those without any history of laryngeal injury may not benefit from this research.
What this research studies
This research investigates the biological processes behind voice disorders caused by the atrophy of intrinsic laryngeal muscles. It aims to uncover how signaling events in the vocal fold mucosa contribute to muscle atrophy, which could lead to better treatment strategies for affected patients. The study will explore the relationship between mucosal injury and muscle function, focusing on specific signaling proteins that may play a role in these conditions. By examining both acute and chronic injuries, the research seeks to provide a comprehensive understanding of the mechanisms involved in voice disorders.
Why it matters
Potential benefit: If successful, this research could lead to improved therapeutic strategies for patients suffering from voice disorders due to vocal fold muscle atrophy.
How similar studies have gone: While the specific approach of linking mucosal injury to muscle atrophy in the vocal folds is innovative, similar research in other muscle systems has shown promising results.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Branski, Ryan Comfort — New York University School of Medicine
- Study coordinator: Branski, Ryan Comfort
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.