Understanding Vitamin K and D for Brain Health in Older Adults

Vitamin K and D and Cognitive Impairment in Older Adults

['FUNDING_R01'] · TUFTS UNIVERSITY BOSTON · NIH-11075304

This work explores how vitamins K and D might protect the brain and support thinking abilities in older individuals.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorTUFTS UNIVERSITY BOSTON (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11075304 on ClinicalTrials.gov

What this research studies

Many older adults don't get enough vitamin K and D, and these nutrients play important roles in brain health. This project looks at how levels of these vitamins relate to brain structure and function, including memory and movement. Researchers are using information from two ongoing community-based groups of older adults to understand these connections better. The goal is to learn more about how these vitamins might help prevent problems like Alzheimer's disease.

Who could benefit from this research

Good fit: This research focuses on older adults, particularly those participating in existing community-based studies like the Rush Memory and Aging Project (MAP).

Not a fit: Patients not experiencing cognitive decline or those not part of the specific existing cohorts may not directly benefit from this particular research.

Why it matters

Potential benefit: If successful, this work could identify dietary factors that help maintain cognitive function and reduce the risk of Alzheimer's disease and related dementias.

How similar studies have performed: Prior work by these researchers has shown associations between higher brain vitamin K and D levels and better cognitive function, suggesting a promising area for further investigation.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.