Understanding viral sepsis in newborns
EV Sepsis Natural History
This study is looking into viral sepsis in newborns, which is a serious illness caused by certain viruses, to learn more about how it affects babies over time and what signs might indicate a more severe illness, with the goal of helping to create better treatments for these little ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10915386 on NIH RePORTER |
What this research studies
This research investigates neonatal viral sepsis, a serious condition affecting newborns caused by viruses like enteroviruses and human parechoviruses. The study aims to better understand the natural history of this condition, including its long-term effects and the clinical indicators that predict severe outcomes. By analyzing various laboratory biomarkers and clinical data, the research seeks to inform the design of future antiviral treatments that are currently lacking. This work is crucial for improving care and outcomes for affected infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns diagnosed with viral sepsis, particularly those infected with enteroviruses or human parechoviruses.
Not a fit: Patients who are older than 11 years or those with non-viral causes of sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective antiviral treatments for neonatal viral sepsis, improving survival rates and long-term health outcomes for affected infants.
How similar studies have performed: While research on neonatal viral sepsis is limited, understanding the natural history of similar conditions has shown promise in informing treatment approaches.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Kimberlin, David W — University of Alabama at Birmingham
- Study coordinator: Kimberlin, David W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.