Understanding use of multiple substances during pregnancy

A Mixed Methods Exploration of Prenatal Polysubstance Use

NIH-funded research Virginia Commonwealth University · NIH-11260183

This project talks with pregnant and postpartum people who used more than one substance and analyzes national pregnancy survey data to learn common patterns and risks.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11260183 on NIH RePORTER

What this research studies

Researchers will conduct 20 interviews with pregnant or recently postpartum people who used multiple substances during pregnancy to hear about their experiences and behaviors. They will also analyze CDC PRAMS, a large national pregnancy survey, to map current patterns of prenatal polysubstance use across the U.S. Findings from interviews and the survey will be compared to give a fuller picture of how substance combinations, places, and environments relate to use. The combined approach aims to identify real-world patterns that could guide support and prevention efforts.

Who could benefit from this research

Good fit: Ideal candidates are pregnant or recently postpartum people who used two or more substances during pregnancy and are willing to be interviewed about their experiences.

Not a fit: People who are not pregnant or postpartum, or those who used only a single substance during pregnancy, are less likely to benefit directly from participation in this specific project.

Why it matters

Potential benefit: If successful, this work could help shape better outreach, prevention, and support for pregnant people who use multiple substances and inform policies to reduce harm to mothers and babies.

How similar studies have performed: Previous research links single-substance prenatal use with environmental factors, but focused mixed-methods work on prenatal polysubstance patterns is limited, so this approach is relatively novel.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.